| Topical isotretinoin in Darier's disease. | |
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MedLine Citation:
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PMID: 8547046 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Topical 0.05% isotretinoin (Isotrex gel) was used to treat a test patch of skin in 11 patients with Darier's disease. Hyperkeratosis and papules improved in six patients after treatment for 3 months. Erythema, burning and irritation were common adverse effects, and these were severe in three patients, one of whom stopped treatment. Patients with mild Darier's disease may find topical isotretinoin helpful, but it is likely that most patients with widespread disease will require treatment with systemic retinoids. |
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Authors:
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S M Burge; P K Buxton |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: The British journal of dermatology Volume: 133 ISSN: 0007-0963 ISO Abbreviation: Br. J. Dermatol. Publication Date: 1995 Dec |
Date Detail:
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Created Date: 1996-02-20 Completed Date: 1996-02-20 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0004041 Medline TA: Br J Dermatol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 924-8 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Stoke Mandeville Hospital NHS Trust, Aylesbury, Bucks, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Cutaneous Adolescent Adult Darier Disease / drug therapy* Drug Administration Schedule Female Humans Isotretinoin / administration & dosage* Keratolytic Agents / administration & dosage* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Keratolytic Agents; 4759-48-2/Isotretinoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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