Document Detail

Topical immunology of nasal allergy and mucosal IgE antibodies.
MedLine Citation:
PMID:  3977769     Owner:  NLM     Status:  MEDLINE    
In the present study, the in vitro tissue-radioallergosorbent test (t-RAST) was performed in two groups of patients: one with perennial attacks of sneezing, serous hypersecretion and nasal congestion, the other with nasal congestion only. The results obtained were compared with those obtained by a series of conventional allergy tests. We then found that t-RAST provided objective data comparable to those obtained with serum-RAST and that the t-RAST is a reliable means of quantitatively detecting specific IgE antibodies in the nasal mucosa. t-RAST is of special value to diagnosticians because it is able to discern unequivocally and easily those patients with localized nasal allergy.
Y Ohashi; Y Nakai; K Kuroki; J Nakata; K Maruoka; H Ikeoka; N Takeichi; S Kihara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of oto-rhino-laryngology     Volume:  241     ISSN:  0302-9530     ISO Abbreviation:  Arch Otorhinolaryngol     Publication Date:  1985  
Date Detail:
Created Date:  1985-04-05     Completed Date:  1985-04-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0414105     Medline TA:  Arch Otorhinolaryngol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  169-74     Citation Subset:  IM    
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MeSH Terms
Immunoglobulin E / metabolism*
Nasal Mucosa / immunology*
Nasal Provocation Tests
Radioallergosorbent Test
Rhinitis, Allergic, Perennial / diagnosis,  immunology*
Reg. No./Substance:
37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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