Document Detail

Topical anesthesia: a possible treatment method for spasticity.
MedLine Citation:
PMID:  7247657     Owner:  NLM     Status:  MEDLINE    
Topical anesthesia was applied to the skin of the leg and thigh of a hemiparesis patient resulting from embolic infarction in the middle cerebral artery. After application of the anesthesia, the angular displacement of the ankle and knee joints measured during a full gait cycle showed a substantial shift towards normal. This response indicated a reduction in muscle spasticity which was confirmed by clinical tests. Neurophysiologic studies performed on the patient suggested that the reduction in muscular hypertonicity was mediated by reduced cutaneous inputs on the alpha - gamma motoneuron interaction. This conjecture is supported by studies of other investigators performed on animals as well as humans.
M A Sabbahi; C J De Luca; W R Powers
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  62     ISSN:  0003-9993     ISO Abbreviation:  Arch Phys Med Rehabil     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-08-27     Completed Date:  1981-08-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  310-4     Citation Subset:  AIM; IM    
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MeSH Terms
Administration, Topical
Ankle Joint
Benzocaine / administration & dosage,  therapeutic use*
Hemiplegia / drug therapy
Knee Joint
Muscle Spasticity / drug therapy*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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