Document Detail

Topical anesthesia for hysteroscopy in postmenopausal women.
MedLine Citation:
PMID:  9050705     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To evaluate the efficacy and safety of topical anesthesia in reducing pain and the frequency of vasovagal reactions during diagnostic hysteroscopy with endometrial biopsy in postmenopausal women. DESIGN: Randomized, placebo-controlled, double-blind study. SETTING: A university hospital. PATIENTS: Forty-two postmenopausal women undergoing diagnostic hysteroscopy and endometrial biopsy. INTERVENTIONS: Two milliliters of 2% mepivacaine or saline solution was injected transcervically into the uterine cavity before performing the procedures. MEASUREMENTS AND MAIN RESULTS: Pain was evaluated on a visual analog scale, and heart rate and blood pressure were monitored continuously. Anesthesia reduced the pain experienced at hysteroscopy and endometrial biopsy, but not significantly. The frequency of vasovagal reactions was significantly lower in the anesthetized group. CONCLUSIONS: Topical anesthesia effectively prevents the occurrence of vasovagal reactions in postmenopausal women undergoing hysteroscopy and endometrial biopsy.
E Cicinelli; T Didonna; G Fiore; C Parisi; M G Matteo; G Castrovilli
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Journal of the American Association of Gynecologic Laparoscopists     Volume:  4     ISSN:  1074-3804     ISO Abbreviation:  J Am Assoc Gynecol Laparosc     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-04-30     Completed Date:  1997-04-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9417443     Medline TA:  J Am Assoc Gynecol Laparosc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  9-12     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Bari, Piazza Giulio Cesare, 70124 Bari, Italy.
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MeSH Terms
Anesthesia, Local*
Anesthetics, Local
Blood Pressure
Double-Blind Method
Endometrium / pathology
Heart Rate
Hysteroscopy* / adverse effects
Middle Aged
Pain / etiology,  prevention & control
Pain Measurement
Syncope, Vasovagal / etiology,  prevention & control
Reg. No./Substance:
0/Anesthetics, Local; 96-88-8/Mepivacaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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