| Topical analgesia for endometrial biopsy: a randomized controlled trial. | |
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MedLine Citation:
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PMID: 15994627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To estimate whether benzocaine spray applied to the cervix and the endocervical canal before performing office endometrial biopsy improves patient comfort during the procedure. METHODS: Eighty-eight women were randomly assigned to receive either 20% benzocaine spray or placebo to the outside of the cervix and into the endocervical canal before an endometrial biopsy was performed. The main outcome measure was pain during the endometrial biopsy, assessed by a visual analog scale. Statistical analysis was performed using Wilcoxon rank-sum test and Student t test. RESULTS: There were no statistically significant differences between the study group and the control group in mean age, race, parity, body mass index, menopausal status, tenaculum use, or history of chronic pelvic pain. No statistically significant differences were found in median pain scores between the 2 treatment groups. CONCLUSION: Topical benzocaine spray does not appear to offer effective pain control in patients undergoing an endometrial biopsy. LEVEL OF EVIDENCE: I. |
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Authors:
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Jon I Einarsson; Gwendolyn Henao; Amy E Young |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 106 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-07-04 Completed Date: 2005-08-11 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 128-30 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, Landspitali-University Hospital, Reykjavik, Iceland. jonivar@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Adult Aged Anesthetics, Local / administration & dosage* Benzocaine / therapeutic use* Biopsy, Needle / methods* Double-Blind Method Endometrium / pathology* Female Humans Middle Aged Pain / prevention & control Pain Measurement Patient Satisfaction Probability Reference Values Risk Assessment Statistics, Nonparametric Treatment Outcome Uterine Diseases / pathology* |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Local; 94-09-7/Benzocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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