| Topical 5-fluorouracil in the treatment of intraepithelial neoplasia of the vagina. | |
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MedLine Citation:
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PMID: 460749 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twelve patients with vaginal intraepithelial neoplasia received topical therapy with 5% 5-fluorouracil cream. Six patients had carcinoma in situ, 5 had moderate dysplasia, and 1 had mild dysplasia. Five patients responded to 1 treatment course. Six patients required 2, and 1 patient required 3 courses of therapy to respond. Three patients developed recurrent vaginal intraepithelial neoplasia 11-16 months after therapy and were retreated with topical 5-fluorouracil. Vaginal irritation occurred in all patients but was limited to the duration of the treatment course. |
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Authors:
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S C Ballon; J A Roberts; L D Lagasse |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 54 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1979 Aug |
Date Detail:
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Created Date: 1979-09-25 Completed Date: 1979-09-25 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 163-6 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Carcinoma in Situ / drug therapy Female Fluorouracil / administration & dosage*, therapeutic use Humans Neoplasm Recurrence, Local / drug therapy Vaginal Neoplasms / drug therapy* |
| Chemical | |
Reg. No./Substance:
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51-21-8/Fluorouracil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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