Document Detail

Topical 5-aminolaevulinic acid photodynamic therapy for intractable palmoplantar psoriasis.
MedLine Citation:
PMID:  17204099     Owner:  NLM     Status:  MEDLINE    
Photodynamic therapy (PDT) has been reported to be useful in treating non-melanoma skin cancers and a variety of benign skin conditions including psoriasis. However, only two reports of palmoplantar pustular psoriasis (PPP) treated with PDT have been reported. We treated three intractable cases of PPP with PDT, using 20% 5-aminolaevulinic acid and a 630+/-50 nm light-emitting diode device. The power density was 30 mW/cm2 and the fluence was 15 J/cm2. After treatment, all cases showed mild to marked improvement. Topical PDT may be an alternative therapy in the treatment of PPP, but further study is necessary to confirm the effectiveness of topical PDT in PPP.
Ji Yeon Kim; Hee Young Kang; Eun-So Lee; You Chan Kim
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of dermatology     Volume:  34     ISSN:  0385-2407     ISO Abbreviation:  J. Dermatol.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-05     Completed Date:  2007-03-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600545     Medline TA:  J Dermatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  37-40     Citation Subset:  IM    
Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
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MeSH Terms
Aminolevulinic Acid / administration & dosage*
Foot Dermatoses / drug therapy
Hand Dermatoses / drug therapy
Middle Aged
Photosensitizing Agents / administration & dosage*
Psoriasis / drug therapy*
Reg. No./Substance:
0/Photosensitizing Agents; 106-60-5/Aminolevulinic Acid

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