Document Detail

Tophaceous gout in a patient with thalassemia.
MedLine Citation:
PMID:  17043448     Owner:  NLM     Status:  PubMed-not-MEDLINE    
We report a 46-year-old Greek female with thalassemia intermedia, who presented to our hospital with end stage renal disease of unknown etiology and tophaceous gout. In addition, skeletal manifestations characteristic of thalassemia were noted with massive extramedullary hematopoiesis presenting as posterior mediastinal masses. We report the first case in English literature of crystal proven gout in thalassemia intermedia and provide a review of the literature that indicates the relative rarity of gout in this clinical setting, despite evidence of urate overproduction in one report. The long survival and renal insufficiency may have contributed to our patients' tophaceous gout.
Vijayalakshmi Kumar; Barry Gruber
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases     Volume:  9     ISSN:  1076-1608     ISO Abbreviation:  J Clin Rheumatol     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2006-10-17     Completed Date:  2007-07-05     Revised Date:  2008-04-10    
Medline Journal Info:
Nlm Unique ID:  9518034     Medline TA:  J Clin Rheumatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  380-4     Citation Subset:  -    
Division of Rheumatology, State University of New York at Stony Brook, Stony Brook, NY, USA.
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