| Tooth shape formation and tooth renewal: evolving with the same signals. | |
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MedLine Citation:
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PMID: 22949612 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Teeth are found in almost all vertebrates, and they therefore provide a general paradigm for the study of epithelial organ development and evolution. Here, we review the developmental mechanisms underlying changes in tooth complexity and tooth renewal during evolution, focusing on recent studies of fish, reptiles and mammals. Mammals differ from other living vertebrates in that they have the most complex teeth with restricted capacity for tooth renewal. As we discuss, however, limited tooth replacement in mammals has been compensated for in some taxa by the evolution of continuously growing teeth, the development of which appears to reuse the regulatory pathways of tooth replacement. |
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Authors:
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Jukka Jernvall; Irma Thesleff |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Development (Cambridge, England) Volume: 139 ISSN: 1477-9129 ISO Abbreviation: Development Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-09-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8701744 Medline TA: Development Country: England |
Other Details:
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Languages: eng Pagination: 3487-97 Citation Subset: IM |
Affiliation:
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Developmental Biology Program, Institute of Biotechnology, University of Helsinki, PO Box 56, FIN-00014, Finland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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