Document Detail

Too little of a good thing: a paradox of moderate infection control.
MedLine Citation:
PMID:  18552592     Owner:  NLM     Status:  MEDLINE    
Epidemic theory dictates that a reduction in the force of infection by a pathogen is associated with an increase in the average age at which individuals are exposed. For those pathogens that cause more severe disease among hosts of an older age, interventions that limit transmission can paradoxically increase the burden of disease in a population.
Ted Cohen; Marc Lipsitch
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Epidemiology (Cambridge, Mass.)     Volume:  19     ISSN:  1531-5487     ISO Abbreviation:  Epidemiology     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-16     Completed Date:  2008-08-22     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  9009644     Medline TA:  Epidemiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  588-9     Citation Subset:  IM    
Division of Social Medicine and Health Inequalities Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
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MeSH Terms
Age Factors
Bacterial Infections / immunology
Disease Transmission, Infectious / prevention & control*
Environmental Exposure
Food Microbiology
Infection Control / methods*
Grant Support
K08 AI055985-06/AI/NIAID NIH HHS
Comment On:
Epidemiology. 2008 Jul;19(4):581-7   [PMID:  18496469 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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