| Too little of a good thing: a paradox of moderate infection control. | |
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MedLine Citation:
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PMID: 18552592 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Epidemic theory dictates that a reduction in the force of infection by a pathogen is associated with an increase in the average age at which individuals are exposed. For those pathogens that cause more severe disease among hosts of an older age, interventions that limit transmission can paradoxically increase the burden of disease in a population. |
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Authors:
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Ted Cohen; Marc Lipsitch |
Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Epidemiology (Cambridge, Mass.) Volume: 19 ISSN: 1531-5487 ISO Abbreviation: Epidemiology Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-06-16 Completed Date: 2008-08-22 Revised Date: 2010-12-17 |
Medline Journal Info:
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Nlm Unique ID: 9009644 Medline TA: Epidemiology Country: United States |
Other Details:
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Languages: eng Pagination: 588-9 Citation Subset: IM |
Affiliation:
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Division of Social Medicine and Health Inequalities Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. tcohen@hsph.harvard.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Bacterial Infections / immunology Disease Transmission, Infectious / prevention & control* Environmental Exposure Food Microbiology Humans Immunity Immunization Infection Control / methods* Virulence* |
| Grant Support | |
ID/Acronym/Agency:
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K08 AI055985-06/AI/NIAID NIH HHS |
| Comments/Corrections | |
Comment On:
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Epidemiology. 2008 Jul;19(4):581-7
[PMID:
18496469
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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