Document Detail


Too fast, too soon to call it "probiotic".
MedLine Citation:
PMID:  21089729     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Probiotics (bacteria or yeasts) were defined by the Food Agricultural Organization (FAO) and the World Health Organization (WHO) joint report as live microorganisms which when administered in adequate amounts (in food or as a dietary supplement) confer a health benefit on the host. The best-demonstrated potential clinical benefits of probiotic agents, specifically in the pediatric population, are in the prevention and management of acute diarrhea, antibiotic associated diarrhea, and evidence is mounting on their potential benefits in atopic disease, inflammatory bowel conditions, and necrotizing enterocolitis. Their beneficial effects seem to be strain specific, thus, pooling data from different strains may result in misleading conclusions. Because there was no international consensus on methodology to assess efficiency and safety of probiotics, in 2001 the FAO/WHO undertook work to compile and evaluate the scientific evidence on functional and safety aspects of probiotics. International criteria have been developed to formulate unequivocal criteria for probiotic bacterial strains and products that contain them. More recently, the European Food Safety Authority (EFSA) highlighted as critical factors for probiotic health claim submissions genetic typing, internationally recognised naming protocols and evidence of consistency in the final product.
Authors:
V L Miniello; A Colasanto; L Diaferio; I S Galizia; J Jablonska; M A Lauriero; M S Lieggi; G Raimondi; V Santoiemma; G Sarcinella; R Simone; P Torrente
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Minerva pediatrica     Volume:  62     ISSN:  0026-4946     ISO Abbreviation:  Minerva Pediatr.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-11-22     Completed Date:  2010-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400740     Medline TA:  Minerva Pediatr     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  105-7     Citation Subset:  IM    
Affiliation:
Clinica Pediatrica Salvatore Maggiore, Dipartimento di Biomedicina dell'Età Evolutiva, Università degli Studi di Bari.
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MeSH Terms
Descriptor/Qualifier:
Animals
Child, Preschool
Dietary Supplements
Digestive System / microbiology
Drug Approval
Europe
Germ-Free Life
Humans
Infant
Infant Food
Infant, Newborn
Microbial Consortia
Probiotics / therapeutic use*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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