Document Detail

Tonsillectomy and inflammatory bowel disease location.
MedLine Citation:
PMID:  8980938     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Epidemiological studies have found an increased frequency of childhood infections and tonsillectomies in patients with inflammatory bowel disease (IBD). The aim of our study was to test whether particular clinical patterns of IBD could be associated with previous tonsillectomy. METHODS: Two hundred and twenty consecutive IBD patients (100 with Crohn's disease (CD) and 120 with ulcerative colitis (UC)) were prospectively assessed and classified into groups according to disease location. In those with a positive history of tonsillectomy, an ear, nose and throat (ENT) examination was carried out to confirm the diagnosis. RESULTS: Eighty-two IBD patients (37%) underwent tonsillectomy in childhood: 47 out of 100 CD patients (47%), and 35 out of 120 UC patients (29%). Disease location in CD patients affected the ileum in 28, and 21 of them were tonsillectomized (tonsillectomy rate of 75%). Thirty-six patients had an ileocolonic location, and 14 of them had had a tonsillectomy (39%). With disease confined to the colon, only 9 out of 29 patients (31%) had undergone previous tonsillectomy. The higher prevalence of tonsillectomy in patients with CD ileitis was statistically significant (P = 0.0034). No significant differences between groups of UC patients according to the extent of the disease were found. CONCLUSION: The ileum is the most prevalent location of disease in CD patients with previous tonsillectomy.
J Maté-Jimenez; J A Correa-Estañ; M Perez-Miranda; A Gomez-Cedenilla; J M Pajares; R Moreno-Otero
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  8     ISSN:  0954-691X     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-03-19     Completed Date:  1997-03-19     Revised Date:  2009-10-16    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1185-8     Citation Subset:  IM    
Hospital de la Princesa, Servicio de Aparato Digestivo, Universidad Autonoma de Madrid, Spain.
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MeSH Terms
Case-Control Studies
Colitis, Ulcerative / epidemiology*,  pathology
Colon / pathology
Crohn Disease / epidemiology*,  pathology
Ileitis / epidemiology,  pathology
Ileum / pathology
Prospective Studies
Tonsillectomy* / adverse effects,  statistics & numerical data
Comment In:
Eur J Gastroenterol Hepatol. 1997 May;9(5):543-4   [PMID:  9187892 ]

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