Document Detail

Tongue-muscle training by intraoral electrical neurostimulation in patients with obstructive sleep apnea.
MedLine Citation:
PMID:  15124719     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVES: To investigate the efficacy of tongue-muscle training by electrical neurostimulation of the upper-airway muscles as an alternative therapy option for obstructive sleep apnea syndrome. DESIGN: A randomized, placebo-controlled, double-blind study. SETTING: Department of pneumology and sleep laboratory, University of Witten/Herdecke, Germany. PATIENTS: 67 patients with an apnea-hypopnea index of 10 to 40 per hour were randomly assigned to 2 groups: a treatment group of 33 patients (mean age, 50.8 +/- 12.1 years; mean body mass index, 29.1 +/- 4.4 kg/m2) and a placebo group of 34 patients (mean age, 53.3 +/- 11.3 years; mean body mass index, 28.9 +/- 4.9 kg/m2). Fifty-seven patients completed the study. INTERVENTIONS: Tongue-muscle training during the daytime for 20 minutes twice a day for 8 weeks. MEASUREMENTS AND RESULTS: Treatment efficacy was examined by polysomnography. Snoring, but not apnea-hypopnea index, improved with stimulation (snoring baseline, 63.9 +/- 23.1 epochs per hour; stimulation training, 47.5 +/- 31.2; P < .05) but not with placebo training (snoring baseline, 62.4 +/- 26.1 epochs per hour; placebo, 62.1 +/- 23.8; NS.). CONCLUSIONS: Although tongue-muscle training cannot generally be recommended for the treatment of sleep apnea, the method has proven to be effective in the treatment of snoring.
Winfried J Randerath; Wolfgang Galetke; Ulrike Domanski; Rolf Weitkunat; Karl-Heinz Ruhle
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Sleep     Volume:  27     ISSN:  0161-8105     ISO Abbreviation:  Sleep     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-05-04     Completed Date:  2004-08-03     Revised Date:  2009-01-29    
Medline Journal Info:
Nlm Unique ID:  7809084     Medline TA:  Sleep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  254-9     Citation Subset:  IM    
Bethanien Hospital, Clinic for Pneumology and Allergology, Center of Sleep Medicine and Ventilatory Care, University Witten/Herdecke, Germany.
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MeSH Terms
Body Mass Index
Double-Blind Method
Electric Stimulation / instrumentation
Middle Aged
Muscle, Skeletal / physiology*
Severity of Illness Index
Sleep Apnea, Obstructive / diagnosis,  prevention & control*
Teaching / methods*
Tongue / physiology*
Comment In:
Sleep. 2004 Aug 1;27(5):1026-7; author reply 1028-9   [PMID:  15453565 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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