| Tomotherapy for neurofibromatosis Type 2: case report and review of the literature. | |
| | |
MedLine Citation:
|
PMID: 20335436 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Neurofibromatosis 2 (NF2) results in multiple central nervous system tumours. In this case report, the patient has one vestibular schwannoma, one trigeminal schwannoma and two meningiomas developed before the age of 30. Aiming to treat three targets at one fraction with minimal interaction and overlapping doses to normal tissue, the sophisticated equipment of tomotherapy was utilised for frameless stereotaxy; tomotherapy delivered intensity-modulated, rotational radiation therapy using a fan-beam delivery. Daily CT scans with the inbuilt CT scanner were also performed as part of the image-guided radiotherapy. The course of fractionated stereotactic radiotherapy consisted of eight fractions given three times per week with an overall treatment time of 17 days. For the meningioma over left parietal vertex, 4.5 Gy per fraction was given at 36 Gy/8 Fr/17 days. For the meningioma over anterior cerebral falx, 4 Gy per fraction was given at 32 Gy/8 Fr/17 days. For the two schwannomas as one target, 5 Gy per fraction was given at 40 Gy/8 Fr/17 days. The acute effect of the treatment was alopecia and mild headache. Subsequent follow-up confirmed clinical improvement. This is the first reported case of clinical experience with tomotherapy in the management of NF2. |
| | |
Authors:
|
H-H Lee; S-L Lian; C-J Huang; M-Y Huang |
Related Documents
:
|
20056016 - Schistosoma japonicum infection and rectal carcinoid tumour: underreported coincidence ... 8729506 - Schwannoma of the posterior pharyngeal wall: a case report. 12581066 - Primary parenchymal cerebral cystic haemangiopericytoma: a 5-year follow up of disease ... 21327836 - Aspergillus lung disease in patients with sarcoidosis: a case series and review of the ... 13679126 - Bilateral cerebrovascular accidents in incontinentia pigmenti. 11305466 - Prospective cohort studies of shigellosis during military field training. |
Publication Detail:
|
Type: Case Reports; Journal Article; Review |
Journal Detail:
|
Title: The British journal of radiology Volume: 83 ISSN: 1748-880X ISO Abbreviation: Br J Radiol Publication Date: 2010 Apr |
Date Detail:
|
Created Date: 2010-03-25 Completed Date: 2010-06-03 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0373125 Medline TA: Br J Radiol Country: England |
Other Details:
|
Languages: eng Pagination: e74-8 Citation Subset: AIM; IM |
Affiliation:
|
Division of Radiation Oncology, Department of Radiation Oncology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Brain Neoplasms / diagnosis, radiotherapy* Dose Fractionation Female Humans Magnetic Resonance Imaging Meningioma / diagnosis, radiotherapy* Neurilemmoma / diagnosis, radiotherapy Neurofibromatosis 2 / diagnosis, radiotherapy* Neuroma, Acoustic / diagnosis, radiotherapy Radiotherapy, Intensity-Modulated / methods* Tomography, X-Ray Computed Treatment Outcome Trigeminal Nerve Diseases / diagnosis, radiotherapy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Atypical presentation of lymphangioleiomyomatosis as jugular vein thrombosis.
Next Document: Intratendinous ganglion cyst of the semimembranosus tendon.