Document Detail


Tomography and Static-Mechanical Properties of Adherent Cells.
MedLine Citation:
PMID:  22886834     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A tomography approach is used to reconstruct 3D cell shapes and, simultaneously, the shapes/positions of the nuclei within these cells. Subjecting the cells to well-defined microconfinements of various diameters allow for relating the steady-state shapes of cells to their static-mechanical properties. The observed shapes show striking regularities between different cell types and all fit to a model which takes into account the cell membrane, cortical actin and the nucleus.
Authors:
Siowling Soh; Kristiana Kandere-Grzybowska; Goher Mahmud; Sabil Huda; Alexander Z Patashinski; Bartosz A Grzybowski
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-13
Journal Detail:
Title:  Advanced materials (Deerfield Beach, Fla.)     Volume:  -     ISSN:  1521-4095     ISO Abbreviation:  Adv. Mater. Weinheim     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9885358     Medline TA:  Adv Mater     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd, Illinois 60208, USA.
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