Document Detail


Tolosa-Hunt syndrome preceded by facial palsy in a child.
MedLine Citation:
PMID:  21147390     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report on a previously healthy 11-year-old boy with unilateral periorbital mild headache and facial nerve palsy, followed during the next 5 months by recurrent unilateral headaches and subsequent extrinsic paresis of the third cranial nerve and paresis of the sixth cranial nerve, each of which improved with steroids. Cranial magnetic resonance imaging revealed increased thickening of the left cavernous sinus and adjacent structures, with marked gadolinium enhancement. Eight months after the initial signs, he developed left retro-orbital headache that lasted 16 days and was relieved 24 hours after resuming steroid treatment. Recurrent multiple cranial neuropathies, neuroimaging findings, and long-lasting headache that responded to steroids indicated Tolosa-Hunt syndrome, further confirmed by extensive investigation and a long follow-up to exclude other causes. This patient illustrates the complexity of disorders with multiple cranial nerve palsies, and adds to the sparse literature on Tolosa-Hunt syndrome in children, describing the first pediatric case preceded by facial palsy.
Authors:
Alfredo Cerisola; Gabriel González; Cristina Scavone
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  44     ISSN:  1873-5150     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-14     Completed Date:  2011-04-01     Revised Date:  2011-06-27    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  61-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Department of Pediatric Neurology, Tacuarembó Regional Hospital, Tacuarembó, Uruguay. alfredocerisola@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents / therapeutic use
Cavernous Sinus / pathology
Child
Cranial Nerve Diseases / complications,  drug therapy,  pathology
Diplopia / etiology
Facial Paralysis / complications*,  pathology
Headache / etiology
Humans
Magnetic Resonance Imaging
Male
Prednisone / therapeutic use
Tolosa-Hunt Syndrome / complications*,  drug therapy,  pathology
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 53-03-2/Prednisone
Comments/Corrections
Comment In:
Pediatr Neurol. 2011 Jun;44(6):478; author reply 478   [PMID:  21555063 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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