Document Detail

Tolerance of liver biopsy in a tertiary care center: comparison of the percutaneous and the transvenous route in 143 prospectively followed patients.
MedLine Citation:
PMID:  22668874     Owner:  NLM     Status:  Publisher    
BACKGROUND: Transjugular liver biopsy (TJLB) is usually performed when a percutaneous liver biopsy (PLB) is contraindicated. TJLB is an invasive procedure and the patient's tolerance may be variable. AIM: To compare patient tolerance and quality of the biopsy sample between PLB and TJLB. PATIENTS AND METHODS: A total of 143 patients underwent a liver biopsy; of these, 75 underwent TJLB and 68 underwent PLB. To evaluate patient tolerance, we used a visual analog scale that scored the intensity of the symptoms. The length of the biopsy sample and the total number of portal tracts per biopsy were also determined for assessment of biopsy quality. RESULTS: The biopsy sample length was similar in both groups (18.88±8.83 mm on PLB vs. 18.26±10.30 mm on TJLB). No differences were found in the number of portal tracts between the two groups (10.43±8.25 on TJLB vs. 12±10.09 on PLB). Fewer complications were observed in the TJLB group compared with the PLB group (P=0.002).Further, higher degree of pain was reported by patients who underwent PLB compared with patients who underwent TJLB (3.18±3.17 vs. 1.19±2.07); as such, there was a greater need for analgesics on PLB. CONCLUSION: TJLB and PLB techniques provide similar quality of tissue samples; however, TJLB is less painful and therefore better tolerated by patients.
Bogdan Procopet; Christophe Bureau; Sophie Métivier; Janick Selves; Marie Angèle Robic; Camille Christol; Mircea Grigorescu; Jean-Pierre Vinel; Jean-Marie Péron
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-3
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  -     ISSN:  1473-5687     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Departments of aHepato-gastroenterology bPathology, Purpan Hospital, CHU Toulouse cINSERM U858 and University of Toulouse, Toulouse, France dUniversity of Medicine and Pharmacy 'Iuliu Hatieganu', Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Romania.
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