Document Detail

Today or in the past? The origins of ischaemic heart disease.
MedLine Citation:
PMID:  8251205     Owner:  NLM     Status:  MEDLINE    
Recent studies have suggested that regional differences in death rates from ischaemic heart disease (IHD) may result from exposure to poverty in foetal and early infant life. The suggestion is that such influences 'permanently set structures and metabolic processes, so-called programming'. On this theory, current falls in IHD death rates reflect much earlier reductions in poverty. If the theory were correct, the fall in rates would begin with younger age groups and be reinforced only at the pace at which each new birth cohort reached adult life. There is no evidence of such a cohort effect. Rates fell simultaneously over a very brief period in each country and region examined. The results are more compatible with theories involving contemporary lifestyle changes.
D Baker; R Illsley; D Vågerö
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of public health medicine     Volume:  15     ISSN:  0957-4832     ISO Abbreviation:  J Public Health Med     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1994-01-10     Completed Date:  1994-01-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9011205     Medline TA:  J Public Health Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  243-8     Citation Subset:  IM    
School of Social Sciences, University of Bath, UK.
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MeSH Terms
Age Factors
Cohort Effect
Finland / epidemiology
Great Britain / epidemiology
Infant, Newborn
Life Style*
Middle Aged
Myocardial Ischemia / epidemiology*,  etiology,  metabolism,  mortality
Prenatal Exposure Delayed Effects*
Residence Characteristics
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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