| Tocopherol isomer pattern in serum and stool of human following consumption of black currant seed press residue administered in whole grain bread. | |
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MedLine Citation:
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PMID: 19523725 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND & AIMS: Serum gamma-tocopherol is thought to be associated with human health. The dietary influence of tocopherol and fibre-rich black currant seed press residue on serum and stool tocopherol concentration was investigated in a controlled human intervention study. METHODS: Thirty-six women consumed bread enriched with black currant press residue (4 weeks). The resultant faecal and serum tocopherol concentrations were compared with those after a period consuming control bread without press residue and a normal baseline diet. Fibre intake and excretion, antioxidant capacity (TEAC), and vitamin C concentrations in serum and urine were also determined. Samples were obtained with a 5-day standardised diet at the end of each period. RESULTS: The press residue bread lead to significantly increased beta-, gamma-, delta- and total tocopherol intake, serum alpha-, beta-, gamma- and total tocopherol concentration (with and without lipid adjustment), fibre intake and urinary vitamin C concentration compared to control bread (P<0.05). Faecal excretion of total tocopherols and fibre increased compared to baseline (P<0.05). CONCLUSIONS: Fibre intake and excretion influence total tocopherol concentration in lipid-adjusted serum and in stool. The outstandingly high increase of serum gamma-tocopherol concentration through seed press residue consumption could be due to a presumed interruption of the enzymatic tocopherol degradation mechanism by bread constituents. |
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Authors:
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Dorit Helbig; Andreas Wagner; Rainer Schubert; Gerhard Jahreis |
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Publication Detail:
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Type: Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-06-11 |
Journal Detail:
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Title: Clinical nutrition (Edinburgh, Scotland) Volume: 28 ISSN: 1532-1983 ISO Abbreviation: Clin Nutr Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-11-16 Completed Date: 2010-02-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309603 Medline TA: Clin Nutr Country: England |
Other Details:
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Languages: eng Pagination: 662-7 Citation Subset: IM |
Affiliation:
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Friedrich Schiller University of Jena, Department of Nutritional Physiology, Dornburger Strasse 24-29, D-07743 Jena, Germany. |
| Data Bank Information | |
Bank Name/Acc. No.:
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ClinicalTrials.gov/NCT00662766 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antioxidants / analysis Ascorbic Acid / blood, urine Bread* / analysis Diet Dietary Fiber / administration & dosage, metabolism Feces / chemistry* Female Humans Isomerism Ribes / chemistry* Seeds / chemistry* Tocopherols / analysis, blood* Waste Products / analysis* Young Adult gamma-Tocopherol / analysis, blood |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Waste Products; 0/gamma-Tocopherol; 1406-66-2/Tocopherols; 50-81-7/Ascorbic Acid |
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