Document Detail

Tobacco attributable deaths in South Africa.
MedLine Citation:
PMID:  15564624     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: In mid 1998, a question "Was the deceased a smoker five years ago?" was introduced on the newly revised South African death notification form.
DESIGN: A total of 16,230 new death notification forms from 1998 have been coded, and comparison of the prevalence of smoking among those who died of different causes was used to estimate, by case-control comparisons, tobacco attributed mortality in South Africa. Cases comprised deaths from causes known (from other studies) to be causally associated with smoking, and controls comprised deaths from medical conditions expected to be unrelated to smoking. Those who died from external causes, and from diseases strongly related to alcohol consumption, were excluded.
SUBJECTS: Reports were available from 5340 deceased adults (age 25+), whose smoking status was given by a family member.
RESULTS: Significantly increased risks were found for deaths from tuberculosis (odds ratio (OR) 1.61, 95% confidence interval (CI) 1.23 to 2.11), chronic obstructive pulmonary disease (COPD) (OR 2.5, 95% CI 1.9 to 3.4), lung cancer (OR 4.8, 95% CI 2.9 to 8.0), other upper aerodigestive cancer (OR 3.0, 95% CI 1.9 to 4.9) and ischaemic heart disease (OR 1.7, 95% CI 1.2 to 2.3).
CONCLUSION: If smokers had the same death rate as non-smokers, 58% of lung cancer deaths, 37% of COPD deaths, 20% of tuberculosis deaths, and 23% of vascular deaths would have been avoided. About 8% of all adult deaths in South Africa (more than 20 000 deaths a year) were caused by smoking.
F Sitas; M Urban; D Bradshaw; D Kielkowski; S Bah; R Peto
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Tobacco control     Volume:  13     ISSN:  1468-3318     ISO Abbreviation:  Tob Control     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-11-26     Completed Date:  2005-02-14     Revised Date:  2014-03-17    
Medline Journal Info:
Nlm Unique ID:  9209612     Medline TA:  Tob Control     Country:  England    
Other Details:
Languages:  eng     Pagination:  396-9     Citation Subset:  IM    
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MeSH Terms
Case-Control Studies
Cause of Death
Digestive System Neoplasms / mortality
Lung Diseases, Obstructive / mortality
Lung Neoplasms / mortality
Middle Aged
Myocardial Ischemia / mortality
Odds Ratio
Respiratory Tract Neoplasms / mortality
Risk Factors
Smoking / adverse effects,  mortality*
South Africa / epidemiology
Tuberculosis, Pulmonary / mortality
Grant Support
10293//Cancer Research UK

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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