| To what extent does increased dietary fiber improve glucose and lipid metabolism in patients with noninsulin-dependent diabetes mellitus (NIDDM)? | |
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MedLine Citation:
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PMID: 3002163 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study assesses the impact of variations in the amount of fiber in high carbohydrate diets on carbohydrate and lipid metabolism in NIDDM. The amount and source of carbohydrate, and source of dietary fiber, were held constant. Two 4-wk diet periods were randomly assigned and all subjects completed both dietary periods. Diets were identical in the proportion of carbohydrate, fat, protein, P/S ratio, and cholesterol. The normal fiber diet contained 11 g/1000 kcal, while the high fiber diet contained 27 g/1000 kcal. The results showed no significant difference in fasting plasma glucose and insulin, day-long glucose and insulin, fasting hemoglobin AIc, or 24 h urinary glucose. Fasting plasma triglyceride and VLDL-triglyceride, as well as fasting plasma cholesterol, LDL-cholesterol, and HDL-cholesterol were also unchanged. In conclusion, an increase in the fiber content from 11 to 27 g/1000 kcal did not lead to measurable improvements in overall plasma glucose, insulin, or lipid metabolism. |
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Authors:
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C B Hollenbeck; A M Coulston; G M Reaven |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 43 ISSN: 0002-9165 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 1986 Jan |
Date Detail:
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Created Date: 1986-02-06 Completed Date: 1986-02-06 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 16-24 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Glucose / analysis Cholesterol / blood Diabetes Mellitus, Type 2 / metabolism* Dietary Fiber / pharmacology* Fasting Glucose / metabolism* Humans Insulin / blood Lipid Metabolism* Lipoproteins / blood Middle Aged Triglycerides / blood |
| Grant Support | |
ID/Acronym/Agency:
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HL-08506/HL/NHLBI NIH HHS; RR-70-22/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Lipoproteins; 0/Triglycerides; 11061-68-0/Insulin; 50-99-7/Glucose; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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