Document Detail

To close or not to close: PFO, sex and cerebrovascular events.
MedLine Citation:
PMID:  17197717     Owner:  NLM     Status:  MEDLINE    
We report on 2 patients with cerebrovascular events associated with sexual activity and PFO who subsequently underwent endovascular patent foramen ovale (PFO) closure. The concurrence of sexual activity (a Valsalva equivalent) at symptom onset, together with supporting data, prior paradoxical embolus in 1 case, elevated D-dimer in another, supported paradoxical embolization as the most likely mechanism of the cerebrovascular events. These cases emphasize that clinicians evaluating patients for PFO closure should explicitly inquire about sexual activity at stroke onset.
Toby Ferguson; Lauren H Sansing; Howard Herrmann; Brett Cucchiara
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  18     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2007-01-01     Completed Date:  2007-02-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E292-3     Citation Subset:  IM    
Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
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MeSH Terms
Embolism, Paradoxical / complications,  physiopathology,  surgery
Heart Septal Defects, Atrial / complications*,  physiopathology*,  surgery
Middle Aged
Sexual Behavior*
Stroke / etiology*,  prevention & control*
Valsalva Maneuver

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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