| Tn7 transposition: two transposition pathways directed by five Tn7-encoded genes. | |
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MedLine Citation:
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PMID: 2834269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The bacterial transposon Tn7 is capable of high-frequency transposition to a specific site in the Escherichia coli chromosome, attTn7, and of low-frequency transposition to sites other than attTn7. Using an in vitro insertional mutagenesis procedure, we have identified and characterized five tns (Tn seven) genes that are essential for Tn7 transposition. Three of these genes, tnsA, tnsB, and tnsC, are required, but are not sufficient, for all Tn7 transposition events. In addition, tnsD is specifically required for transposition to attTn7, whereas tnsE is specifically required for transposition to other sites. Thus, Tn7 is an elaborate transposon that encodes two distinct but overlapping transposition pathways. |
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Authors:
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C S Waddell; N L Craig |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Genes & development Volume: 2 ISSN: 0890-9369 ISO Abbreviation: Genes Dev. Publication Date: 1988 Feb |
Date Detail:
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Created Date: 1988-06-02 Completed Date: 1988-06-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8711660 Medline TA: Genes Dev Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 137-49 Citation Subset: IM |
Affiliation:
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Department of Biochemistry and Biophysics, University of California, San Francisco 94143-0552. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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DNA Transposable Elements* Escherichia coli / genetics* Gene Amplification Genes, Bacterial* Mutation Plasmids |
| Chemical | |
Reg. No./Substance:
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0/DNA Transposable Elements |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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