Document Detail


Influence of bisphosphonates in orthodontic therapy: Systematic review.
MedLine Citation:
PMID:  20546824     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The objective of this paper was to analyse the effects of bisphosphonates and their influence on orthodontic therapy. DATA/SOURCES: The literature was systematically reviewed using PubMed/Medline, Scopus, Ebsco Host, Scirus and Cochrane databases up to December 31, 2008. STUDY SELECTION: Articles were independently selected by two different researchers based on previously established inclusion and exclusion criteria, finding a good concordance (kappa index of 0.862). The methodological quality of the reviewed papers was assessed. The search strategy identified 205 titles. Thirteen articles were selected after application of the inclusion/exclusion criteria, and only one of these had a high methodological quality. Bisphosphonate applications in orthodontic therapy were divided between two main groups: tooth movement and skeletal relapse. CONCLUSIONS: Topical or systemic application of bisphosphonates decreases orthodontic tooth movement and reduces orthodontic tooth movement relapse and skeletal relapse after maxillary expansion or mandibular distraction and similar procedures. Further longer-term studies are required to assess possible adverse effects after bisphosphonate treatment for these purposes.
Authors:
Alejandro Iglesias-Linares; Rosa-María Yáñez-Vico; Enrique Solano-Reina; Daniel Torres-Lagares; Miguel Angel González Moles
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-06-08
Journal Detail:
Title:  Journal of dentistry     Volume:  38     ISSN:  1879-176X     ISO Abbreviation:  J Dent     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-10-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0354422     Medline TA:  J Dent     Country:  England    
Other Details:
Languages:  eng     Pagination:  603-11     Citation Subset:  D; IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
School of Dentistry, University of Seville, Spain. aiglesiaslinares@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Bone Density Conservation Agents / pharmacology*
Bone Remodeling / drug effects*
Diphosphonates / pharmacology*
Humans
Mandibular Advancement
Orthodontic Anchorage Procedures
Orthodontics, Corrective*
Osteogenesis, Distraction
Palatal Expansion Technique
Recurrence / prevention & control
Root Resorption / prevention & control
Tooth Movement
Chemical
Reg. No./Substance:
0/Bone Density Conservation Agents; 0/Diphosphonates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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