| Titanium-nitride-oxide coated stents versus paclitaxel-eluting stents in acute myocardial infarction: a 12-months follow-up report from the TITAX AMI trial. | |
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MedLine Citation:
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PMID: 19110789 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: The aim of this study was to evaluate the effectiveness of titanium-nitride-oxide (TITANOX)-coated stent and paclitaxel-eluting stent (PES) in patients presenting with acute myocardial infarction (MI). METHODS AND RESULTS: A total of 425 patients presenting with acute non-ST-elevation MI or ST-elevation MI were randomly assigned to receive TITANOX-coated stent or PES. The primary end point was a composite of MI, target lesion revascularisation (TLR) or death from cardiac causes. At 12 months, there was no significant difference between patients receiving TITANOX-coated stent or PES in the rates of primary end point (10.3% vs. 12.8%, P=0.5), MI (4.2% vs. 8.1%, P=0.1), or TLR (9.3% vs. 7.1%, P=0.5), respectively. The incidence of stent thrombosis, defined according to Academic Research Consortium classification, was significantly lower in the TITANOX group compared to the PES group (0.9% vs. 4.3%, P=0.03). CONCLUSIONS: TITANOX-coated stent and PES resulted in comparable clinical outcomes during 12 months follow-up among patients treated for acute MI. |
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Authors:
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Pasi P Karjalainen; Antti Ylitalo; Matti Niemelä; Kari Kervinen; Timo Mäkikallio; Mikko Pietili; Jussi Sia; Petri Tuomainen; Kai Nyman; K E Juhani Airaksinen |
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Publication Detail:
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Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology Volume: 4 ISSN: 1774-024X ISO Abbreviation: - Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-12-29 Completed Date: 2009-02-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101251040 Medline TA: EuroIntervention Country: France |
Other Details:
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Languages: eng Pagination: 234-41 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Satakunta Central Hospital, Pori, Finland. pasi.karjalainen@satshp.fi |
| Data Bank Information | |
Bank Name/Acc. No.:
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ClinicalTrials.gov/NCT00495664 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Transluminal, Percutaneous Coronary* Antineoplastic Agents, Phytogenic / administration & dosage Disease-Free Survival Drug-Eluting Stents* Female Follow-Up Studies Humans Incidence Male Middle Aged Myocardial Infarction / epidemiology, therapy* Paclitaxel / administration & dosage* Recurrence Risk Factors Thrombosis / prevention & control Titanium* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents, Phytogenic; 0/titanium-nitride-oxide; 33069-62-4/Paclitaxel; 7440-32-6/Titanium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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