| Tissue viability imaging: mapping skin erythema. | |
| | |
MedLine Citation:
|
PMID: 19152573 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Tissue Viability Imaging (TiVi) is an emerging bioengineering technology intended for two-dimensional mapping of skin erythema and blanching. Before TiVi can be effectively used in studies of diseased or damaged skin, the variability in normal skin red blood cell concentration (RBC(conc)) requires evaluation. OBJECTIVE: To demonstrate how TiVi maps spatial and temporal variations in normal skin RBC(conc) at the dorsal side of the hand at rest and during post-occlusive hyperemia. METHODS: Short-term and day-to-day variations in skin RBC(conc) were quantified at the dorsal side of the hand in four healthy volunteers at rest. In a separate study, the increase in skin RBC(conc) was recorded during post-occlusive hyperemia. RESULTS: A lower skin RBC(conc) (179-184 TiVi units) was observed at the back of the hand and base of the thumb compared with areas adjacent to the nailfoldfold region of the fingers (190-213 TiVi units). The short-term variation (within 70 s) was <2% in all areas of the dorsal side of the hand, while day-to-day variations were in the range 5-7% in the back of the hand and up to 10% in areas adjacent to the nailfold region. In the post-occlusive hyperemia phase, up to a 60% increase in skin RBC(conc) was observed in the early part of the reactive hyperemia phase. This increase in skin RBC(conc) successively decreased but remained about 18% above the pre-occlusion level after 30 min. CONCLUSION: Establishment of healthy skin RBC(conc) reference values is important for the design of versatile test procedures for assessment of skin damage caused by vibration tools, chemical exposure or peripheral vascular disease. |
| | |
Authors:
|
Hongbo Zhai; Heidi P Chan; Sara Farahmand; Gert E Nilsson; Howard I Maibach |
Related Documents
:
|
6428883 - Changes in erythrocyte carbonic anhydrase activity due to physical exercise. 4086193 - The effect of exercise on the total water space and red blood cell volume of the gracil... 408153 - Effect of physical exercise on erythrocyte lipids, biliary cholesterol and bile lithoge... |
Publication Detail:
|
Type: Evaluation Studies; Journal Article |
Journal Detail:
|
Title: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) Volume: 15 ISSN: 1600-0846 ISO Abbreviation: Skin Res Technol Publication Date: 2009 Feb |
Date Detail:
|
Created Date: 2009-01-20 Completed Date: 2009-04-02 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9504453 Medline TA: Skin Res Technol Country: Denmark |
Other Details:
|
Languages: eng Pagination: 14-9 Citation Subset: IM |
Affiliation:
|
Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Dermoscopy
/
instrumentation* Equipment Design Equipment Failure Analysis Erythema / pathology*, physiopathology* Erythrocyte Count / instrumentation*, methods Humans Image Interpretation, Computer-Assisted / instrumentation*, methods Reproducibility of Results Sensitivity and Specificity Spectrum Analysis / instrumentation* Sweden Tissue Survival |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cutaneous bioengineering instrumentation standardization: the Tissue Viability Imager.
Next Document: Comparison of tissue viability imaging and colorimetry: skin blanching.