| Tissue specific delivery of estrone-conjugated siRNAs. | |
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MedLine Citation:
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PMID: 23037688 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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An estrone phosphoramidite, synthesized in a single step, was directly incorporated at the 5' ends of small interfering RNAs (siRNAs). The resulting estrone-conjugated siRNAs readily pass through cellular membranes and down-regulate the target protein, and show specific distributions in vivo. |
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Authors:
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Eun-Kyoung Bang; Eun Mi Jeon; Wanil Kim; Kyung-Ha Lee; Kyong-Tai Kim; Byeang Hyean Kim |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-5 |
Journal Detail:
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Title: Molecular bioSystems Volume: - ISSN: 1742-2051 ISO Abbreviation: Mol Biosyst Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101251620 Medline TA: Mol Biosyst Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Chemistry, BK School of Molecular Science, Pohang University of Science and Technology, Pohang 790-784, Korea. bhkim@postech.ac.kr. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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