| Tissue reactivity to poliglecaprone 25 in the feline linea alba. | |
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MedLine Citation:
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PMID: 10582744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To use poliglecaprone 25 for all ligations and closure in routine feline ovariohysterectomies and evaluate maintenance of tissue approximation and tissue reaction to the suture. STUDY DESIGN: Prospective, descriptive study. ANIMALS: Twenty four female cats. METHODS: Ovariohysterectomies were performed in all cats. Abdominal incisions were inspected on days 1, 3, 7, 14, and 28 for dehiscence and swelling. All cats were euthanatized postoperatively, group 1 on day 7; group 2 on day 14; and group 3 on day 28. The peritoneal cavity was inspected for adhesions and all abdominal incisions were collected en bloc. Each linea alba was histologically evaluated and the inflammatory reaction was characterized. RESULTS: Dehiscence did not occur in any of the 24 cats. The incisional swelling on day 1 was significantly smaller than on day 7, and the swelling on day 14 was significantly smaller than on days 1, 3, and 7 (P < .05). Intra-abdominal adhesions were found in all groups with the greatest number associated with the peritoneum at the incision site. Tissue reactions in group 1 were pyogranulomatous or fibromononuclear, group 2 were granulomatous or fibromononuclear, and group 3 were pyogranulomatous, granulomatous, fibromononuclear or fibrous. Eosinophilic infiltration was seen in 3 of the 8 cats in group 1. CONCLUSIONS: Incisional swelling and inflammatory reactions seen with poliglecaprone 25 were consistent with those anticipated after implantation of suture in a surgically created wound. CLINICAL RELEVANCE: Poliglecaprone 25 appears to be an acceptable suture for use in feline ovariohysterectomy. It causes a relatively short-lived inflammatory response. |
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Authors:
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A Runk; S W Allen; E A Mahaffey |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Veterinary surgery : VS Volume: 28 ISSN: 0161-3499 ISO Abbreviation: Vet Surg Publication Date: 1999 Nov-Dec |
Date Detail:
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Created Date: 1999-12-30 Completed Date: 1999-12-30 Revised Date: 2011-04-25 |
Medline Journal Info:
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Nlm Unique ID: 8113214 Medline TA: Vet Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 466-71 Citation Subset: IM |
Affiliation:
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Department of Small Animal Medicine, College of Veterinary Medicine, The University of Georgia, Athens, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdomen Animals Cats / surgery* Dioxanes / adverse effects* Female Hysterectomy / methods, veterinary Inflammation / chemically induced, veterinary Omentum Ovariectomy / veterinary Peritoneal Diseases / veterinary Polyesters / adverse effects* Postoperative Period Prospective Studies Skin / drug effects*, pathology Surgical Wound Dehiscence / veterinary Suture Techniques / veterinary Sutures / veterinary* Tissue Adhesions / veterinary |
| Chemical | |
Reg. No./Substance:
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0/Dioxanes; 0/Polyesters; 41706-81-4/glycolide E-caprolactone copolymer |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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