Document Detail


Tissue metabolomics of hepatocellular carcinoma: tumor energy metabolism and the role of transcriptomic classification.
MedLine Citation:
PMID:  23463346     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: Tissue metabolomics yielded precise biochemical information regarding HCC tumor metabolic remodeling from mitochondrial oxidation to aerobic glycolysis and the impact of molecular subtypes on this process.
Authors:
Diren Beyoğlu; Sandrine Imbeaud; Olivier Maurhofer; Paulette Bioulac-Sage; Jessica Zucman-Rossi; Jean-François Dufour; Jeffrey R Idle
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2013-05-08
Journal Detail:
Title:  Hepatology (Baltimore, Md.)     Volume:  58     ISSN:  1527-3350     ISO Abbreviation:  Hepatology     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-26     Completed Date:  2013-08-30     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8302946     Medline TA:  Hepatology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  229-38     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 American Association for the Study of Liver Diseases.
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Hepatocellular / classification,  metabolism*
Energy Metabolism*
Gas Chromatography-Mass Spectrometry
Gene Expression Profiling / methods
Humans
Lipid Metabolism / physiology
Liver / metabolism*
Liver Neoplasms / classification,  metabolism*
Metabolomics*
Transcriptome*
Tumor Markers, Biological / metabolism
Grant Support
ID/Acronym/Agency:
U19 AI067773/AI/NIAID NIH HHS; U19 AI067773-07/08/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Tumor Markers, Biological
Comments/Corrections
Comment In:
Nat Rev Gastroenterol Hepatol. 2013 Apr;10(4):199-200   [PMID:  23358397 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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