Document Detail


Tissue engineering for neuromuscular disorders of the gastrointestinal tract.
MedLine Citation:
PMID:  23322989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The digestive tract is designed for the optimal processing of food that nourishes all organ systems. The esophagus, stomach, small bowel, and colon are sophisticated neuromuscular tubes with specialized sphincters that transport ingested food-stuffs from one region to another. Peristaltic contractions move ingested solids and liquids from the esophagus into the stomach; the stomach mixes the ingested nutrients into chyme and empties chyme from the stomach into the duodenum. The to-and-fro movement of the small bowel maximizes absorption of fat, protein, and carbohydrates. Peristaltic contractions are necessary for colon function and defecation.
Authors:
Kenneth L Koch; Khalil N Bitar; John E Fortunato
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  18     ISSN:  2219-2840     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-01-16     Completed Date:  2013-12-12     Revised Date:  2014-05-20    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  6918-25     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Absorption
Animals
Bioengineering / methods
Colon / pathology
Esophagus / pathology
Gastrointestinal Diseases / therapy*
Humans
Intestine, Small / pathology
Neuromuscular Diseases / therapy*
Peristalsis
Regenerative Medicine / methods
Stomach / pathology
Tissue Engineering / methods*
Grant Support
ID/Acronym/Agency:
1RC1DK087151/DK/NIDDK NIH HHS; R01DK071614/DK/NIDDK NIH HHS; U01 DK073975-01/DK/NIDDK NIH HHS
Comments/Corrections

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