Document Detail

Tissue engineering in urethral reconstruction--an update.
MedLine Citation:
PMID:  23042444     Owner:  NLM     Status:  MEDLINE    
The field of tissue engineering is rapidly progressing. Much work has gone into developing a tissue engineered urethral graft. Current grafts, when long, can create initial donor site morbidity. In this article, we evaluate the progress made in finding a tissue engineered substitute for the human urethra. Researchers have investigated cell-free and cell-seeded grafts. We discuss different approaches to developing these grafts and review their reported successes in human studies. With further work, tissue engineered grafts may facilitate the management of lengthy urethral strictures requiring oral mucosa substitution urethroplasty.
Altaf Mangera; Christopher R Chapple
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Publication Detail:
Type:  Journal Article; Review     Date:  2012-10-08
Journal Detail:
Title:  Asian journal of andrology     Volume:  15     ISSN:  1745-7262     ISO Abbreviation:  Asian J. Androl.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-07     Completed Date:  2013-06-06     Revised Date:  2013-09-17    
Medline Journal Info:
Nlm Unique ID:  100942132     Medline TA:  Asian J Androl     Country:  China    
Other Details:
Languages:  eng     Pagination:  89-92     Citation Subset:  IM    
Department of Urology Research, Sheffield Teaching Hospitals NHS Trust, Royal Hallamshire Hospital, Sheffield S10 2JF, UK.
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MeSH Terms
Mouth Mucosa / transplantation
Reconstructive Surgical Procedures / methods*
Tissue Engineering / methods*
Urethra / surgery
Urethral Stricture / surgery*

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