| Tissue-engineering bone from omentum. | |
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MedLine Citation:
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PMID: 20942265 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tissue engineering of bone is an interesting field of research. Many approaches to bone tissue engineering such as from bone marrow stromal cells in vitro have been reported. Furthermore, a model of vascularized tissue-engineered bone flap has been reported. However, there has been no report of bone tissue engineering using omentum. We present a study of tissue engineering of bone from omentum in a rabbit model. The omentum, which was elevated based on the right gastroepiploic vessels, was wrapped by the periosteum from cranial bone in the abdomen of rabbits. We harvested the omentum thus wrapped 1, 2, 4, 6, 8, 12, or 24 weeks after surgery. Within 1 week after surgery, woven bone was formed and clusters of osteoblasts were observed. At 8 weeks, medullization, including the presence of granulocytes, was confirmed. This technique might prove useful for creating tissue-engineered bone flaps for reconstructive surgery. |
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Authors:
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Yuzuru Kamei; Kazuhiro Toriyama; Toru Takada; Shunjiro Yagi |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Nagoya journal of medical science Volume: 72 ISSN: 0027-7622 ISO Abbreviation: Nagoya J Med Sci Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-10-14 Completed Date: 2010-11-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0412011 Medline TA: Nagoya J Med Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 111-7 Citation Subset: IM |
Affiliation:
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Department of Plastic and Reconstructive Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. joe@med.nagoya-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bone and Bones / cytology* Models, Animal Omentum / cytology* Rabbits Stromal Cells / cytology* Tissue Engineering / methods* Tissue and Organ Harvesting / methods* |
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