| Tissue culture of some lichens and screening of their antioxidant, antityrosinase and antibacterial properties. | |
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MedLine Citation:
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PMID: 17628467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lichen species Usnea ghattensis, Heterodermia podocarpa, Arthothelium awasthii and Parmotrema tinctorum have been cultured in vitro and screened for their antioxidant, antimicrobial and antityrosinase potential using different assay systems. The methanol extract of lichens showed antioxidant, antimicrobial and antityrosinase activities according to the order Usnea ghattensis > Arthothelium awasthii > Heterodermia podocarpa > Parmotrema tinctorum. The IC(50) values for the antioxidant and antityrosinase activities of U. ghattensis and A. awasthii were less than or equivalent to that of standard antioxidants and tyrosinase inhibitors. The methanol extracts of the lichen cultures Usnea ghattensis and Arthothelium awasthii were effective against Bacillus licheniformis, Bacillus megaterium, Bacillus subtilis and Staphylococcus aureus. The minimum inhibitory concentration (MIC) of the extract was found to be between 5 and 10 microg extract/mL. The results suggested that the extract of lichen cultures, U. ghattensis and A. awasthii, could be of use as an easily accessible source of natural antioxidants, tyrosinase inhibitory and antimicrobial properties as possible food supplements or in the pharmaceutical industry. |
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Authors:
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B C Behera; Neeraj Verma; Anjali Sonone; Urmila Makhija |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Retracted Publication |
Journal Detail:
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Title: Phytotherapy research : PTR Volume: 21 ISSN: 0951-418X ISO Abbreviation: Phytother Res Publication Date: 2007 Dec |
Date Detail:
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Created Date: 2007-12-06 Completed Date: 2008-04-03 Revised Date: 2008-07-30 |
Medline Journal Info:
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Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: England |
Other Details:
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Languages: eng Pagination: 1159-70 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2007 John Wiley & Sons, Ltd. |
Affiliation:
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Plant Science Division, Agharkar Research Institute, G. G. Agarkar Road, Pune-411004, India. bcbehera2002@yahoo.co.in |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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analysis* Biological Products / chemistry, pharmacology Culture Techniques Flavonoids / analysis Free Radical Scavengers / analysis* Inhibitory Concentration 50 Lichens / chemistry*, growth & development Lipid Peroxidation / drug effects Monophenol Monooxygenase / antagonists & inhibitors* Phenols / analysis Polysaccharides / analysis Proteins / analysis |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Biological Products; 0/Flavonoids; 0/Free Radical Scavengers; 0/Phenols; 0/Polysaccharides; 0/Proteins; 0/polyphenols; EC 1.14.18.1/Monophenol Monooxygenase |
| Comments/Corrections | |
Retraction In:
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Williamson EM. Phytother Res. 2008 May;22(5):708
[PMID:
18444246
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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