| Tissue-engineered tracheal transplantation. | |
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MedLine Citation:
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PMID: 20061996 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Regenerative medicine offers new tools with which to tackle disorders for which there is currently no good therapeutic option. The trachea is an ideal organ in which to explore the clinical potential of tissue engineering because severe large airway disease is poorly managed by conventional treatments, and the success of a graft is determined only by its ability to conduct air lifelong: that is, whether it can become a sustainable biological conduit. We define the component parts of tissue engineering and review the experimental methods used to produce airway implants to date, including a recent successful, first-in-man experience. |
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Authors:
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Silvia Baiguera; Martin A Birchall; Paolo Macchiarini |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Transplantation Volume: 89 ISSN: 1534-6080 ISO Abbreviation: Transplantation Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-10 Completed Date: 2010-04-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0132144 Medline TA: Transplantation Country: United States |
Other Details:
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Languages: eng Pagination: 485-91 Citation Subset: IM |
Affiliation:
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BIOAIR (Laboratory of Biomolecular and Bioengineering Airways), University of Florence, Florenz, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bronchomalacia / surgery* Chondrocytes / transplantation Epithelial Cells / transplantation Female Humans Regeneration / physiology Tissue Engineering / methods*, trends Trachea / cytology, transplantation* Transplantation Tolerance Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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