Document Detail


Tissue Doppler echocardiography in persons with hypertension, diabetes, or ischaemic heart disease: the Copenhagen City Heart Study.
MedLine Citation:
PMID:  19176536     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: To test the hypothesis that echocardiographic tissue Doppler imaging (TDI) reveals reduced myocardial function in hypertension, diabetes, and ischaemic heart disease (IHD) in the general population. METHODS AND RESULTS: Within a large, community-based population study, cardiac function was evaluated in 1036 participants by both conventional echocardiography and colour TDI. Peak systolic (s') and early diastolic (e') velocities, longitudinal displacement (LD), and the ratio of mitral inflow E-wave to e' (E/e') were measured. TDI revealed significantly impaired parameters of systolic and diastolic cardiac function in hypertension [n = 345; LD 10.1 (+/-standard deviation, SD 2.0 mm), P < 0.001; E/e' 12.4 (x/SD 1.4), P < 0.001], diabetes [n = 65; LD 9.8 (+/-SD 2.2 mm), P < 0.001; E/e' 12.7 (x/SD 1.5), P < 0.001], and IHD [n = 93; LD 9.4 (+/-SD 2.5 mm), P < 0.001; E/e' 13.0 (x/SD 1.5), P < 0.001] compared with controls [n = 533; LD 11.4 (+/-SD 2.0 mm); E/e' 9.0 (x/SD 1.3)]. This pattern remained significant after adjusting for age, sex, body mass index, heart rate, and the results of conventional echocardiography. CONCLUSION: In the general population, persons with hypertension, diabetes, or IHD have impaired cardiac function by TDI independently of the result of conventional echocardiography.
Authors:
Rasmus Mogelvang; Peter Sogaard; Sune A Pedersen; Niels T Olsen; Peter Schnohr; Jan S Jensen
Related Documents :
16277166 - Evaluation of right and left ventricular function using pulsed-wave tissue doppler echo...
15637486 - Quantitative regional analysis of left atrial function by doppler tissue imaging-derive...
17555936 - Transmitral flow patterns and the presence of chronic kidney disease provide independen...
6851026 - Influence of age on wall thickness, cavity dimensions and myocardial contractility of t...
2961246 - Left ventricular hypertrophy and myocardial ischemia in systemic hypertension.
18522786 - Recommendations for performing acetylcholine tests safely: stop dangerous complications...
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-27
Journal Detail:
Title:  European heart journal     Volume:  30     ISSN:  1522-9645     ISO Abbreviation:  Eur. Heart J.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-05-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  England    
Other Details:
Languages:  eng     Pagination:  731-9     Citation Subset:  IM    
Affiliation:
Copenhagen City Heart Study, Epidemiological Research Unit, Bispebjerg Hospital, Copenhagen, Denmark. Rasmus.Mogelvang@get2net.dk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Blood Flow Velocity / physiology
Denmark / epidemiology
Diabetic Angiopathies / physiopathology,  ultrasonography*
Diastole
Echocardiography, Doppler
Female
Humans
Hypertension / physiopathology,  ultrasonography*
Longitudinal Studies
Male
Middle Aged
Myocardial Ischemia / physiopathology,  ultrasonography*
Risk Assessment
Systole
Comments/Corrections
Comment In:
Eur Heart J. 2009 Mar;30(6):642-4   [PMID:  19228715 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Antepartum continuous epidural ropivacaine therapy reduces uterine artery vascular resistance in pre...
Next Document:  Stroke in paroxysmal atrial fibrillation: report from the Stockholm Cohort of Atrial Fibrillation.