Document Detail


Tisseel for management of traumatic postpartum haemorrhage.
MedLine Citation:
PMID:  18985368     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Following the introduction of haemostatic agents, new opportunities are available when facing problematic bleeding. We report the first case of traumatic postpartum hemorrhage successfully controlled with a fibrin sealant. CASE PRESENTATION: 26-year nulliparous patient had a rotational forceps delivery and developed multiple vaginal lacerations. Haemostasis could not be achieved after suturing, vaginal packing and IV tranaxemic acid. She lost approx. 3,500 ml blood and received 4 U transfusion. Tisseel was used as a thin layer on vaginal wall and bleeding settled. She had good recovery and perineum healed well. CONCLUSION: Tisseel consists of a two-component fibrin biomatrix to stop diffuse bleeding. When the tissues are very oedematous, it can be difficult to insert sutures. We tried this innovative option with very effective results. The absence of long-term complications is reassuring and we recommend its use in similarly extreme situations.
Authors:
Jaya Saxena Dhulkotia; M Alazzam; A Galimberti
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Publication Detail:
Type:  Case Reports; Letter     Date:  2008-11-05
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  279     ISSN:  1432-0711     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-01-26     Completed Date:  2009-04-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  437-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fibrin Tissue Adhesive / therapeutic use*
Humans
Postpartum Hemorrhage / therapy*
Pregnancy
Chemical
Reg. No./Substance:
0/Fibrin Tissue Adhesive

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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