Document Detail

MedLine Citation:
PMID:  19454115     Owner:  NLM     Status:  In-Data-Review    
INTRODUCTION: Up to 18% of people in industrialised societies have mild tinnitus, which severely affects daily life in 0.5% of people. Tinnitus can be associated with hearing loss, acoustic neuromas, drug toxicity, ear diseases, and depression. Tinnitus can last for many years, and can interfere with sleep and concentration. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for chronic tinnitus? We searched: Medline, Embase, The Cochrane Library and other important databases up to December 2006. (BMJ Clinical evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
RESULTS: We found 37 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acamprosate, acupuncture, antidepressant drugs, baclofen, benzodiazepines, carbamazepine, cinnarizine, ear-canal magnets, electromagnetic stimulation, ginkgo biloba, hearing aids, hyperbaric oxygen, hypnosis, lamotrigine, nicotinamide, psychotherapy, tinnitus-masking devices, tinnitus retraining therapy, zinc.
Julian Savage; Stephanie Cook; Angus Wadell
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Publication Detail:
Type:  Journal Article     Date:  2007-08-01
Journal Detail:
Title:  Clinical evidence     Volume:  2007     ISSN:  1752-8526     ISO Abbreviation:  Clin Evid (Online)     Publication Date:  2007  
Date Detail:
Created Date:  2009-05-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101294314     Medline TA:  Clin Evid (Online)     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Gloucestershire Royal Hospital, Gloucester, UK.
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