| Timolol gel versus acetazolamide in the prophylaxis of ocular hypertension after phacoemulsification. | |
| | |
MedLine Citation:
|
PMID: 9379379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To compare postoperative intraocular pressure (IOP) after administration of acetazolamide and timolol following phacoemulsification and intraocular lens implantation. SETTING: Ophthalmic Consultants of Long Island, Rockville Centre, New York, USA. METHODS: Sixty patients were included in a prospective, randomized, masked trial. The patients received either two doses of oral, sustained-release acetazolamide (Diamox Sequels) or a single dose of topical timolol 0.5% gel (Timoptic XE). Intraocular pressure was measured by Goldmann applanation tonometry preoperatively and 1 day postoperatively. RESULTS: Mean preoperative IOP was 16.4 mm Hg. One day postoperatively, it was 19.5 mm Hg in the oral acetazolamide group and 15.9 mm Hg in the timolol gel group. One patient in the acetazolamide group developed significant adverse reactions. CONCLUSION: Prophylactic use of topical timolol 0.5% gel for viscoelastic-induced ocular hypertension after cataract extraction appears to offer better IOP control than oral acetazolamide and has potentially fewer adverse systemic effects. |
| | |
Authors:
|
A J Kanellopoulos; H D Perry; E D Donnenfeld |
Related Documents
:
|
9626919 - Interaction between timolol eyedrops and oral nicardipine or oral diltiazem in healthy ... 7260019 - Quantitative trabeculectomy. 14609909 - Prevention of corticosteroid-induced intraocular pressure elevation using isv-205. 21832209 - Validity of auscultatory and penaz blood pressure measurements during profound heat str... 6746239 - Proptosis and increase of intraocular pressure in voluntary lid fissure widening. 8113009 - Free radicals in retinal and choroidal blood flow autoregulation in the piglet: interac... 7135289 - Tracheal damage after endotracheal intubation: comparison of two types of endotracheal ... 31829 - Cumulative dose-response curves for early evaluation of bronchodilator drugs. 6193349 - Comparison of effects of guanfacine and clonidine on blood pressure, heart rate, urinar... |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of cataract and refractive surgery Volume: 23 ISSN: 0886-3350 ISO Abbreviation: J Cataract Refract Surg Publication Date: 1997 Sep |
Date Detail:
|
Created Date: 1997-11-12 Completed Date: 1997-11-12 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8604171 Medline TA: J Cataract Refract Surg Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1070-4 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, State University of New York, Health Science Center at Brooklyn 11203, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acetazolamide
/
administration & dosage,
adverse effects,
therapeutic use* Adrenergic beta-Antagonists / administration & dosage, adverse effects, therapeutic use* Carbonic Anhydrase Inhibitors / administration & dosage, adverse effects, therapeutic use* Delayed-Action Preparations Double-Blind Method Female Gels Humans Intraocular Pressure Lens Implantation, Intraocular Male Ocular Hypertension / etiology, prevention & control* Phacoemulsification / adverse effects* Premedication Prospective Studies Timolol / administration & dosage, adverse effects, therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
0/Adrenergic beta-Antagonists; 0/Carbonic Anhydrase Inhibitors; 0/Delayed-Action Preparations; 0/Gels; 26839-75-8/Timolol; 59-66-5/Acetazolamide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Anterior chamber contamination during cataract surgery with intraocular lens implantation.
Next Document: Levobunolol 0.5% and timolol 0.5% to prevent intraocular pressure elevation after neodymium:YAG lase...