| Timing of screening for gestational diabetes mellitus in women with moderate and severe obesity. | |
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MedLine Citation:
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PMID: 22085417 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective. We evaluated screening with a diagnostic oral Glucose Tolerance Test earlier than 20 weeks gestation in women with moderate/severe obesity. Design. Prospective observational study. Population. We enrolled 100 women booking for antenatal care in the first trimester at their convenience. Setting. Large university teaching hospital. Methods. Height and weight were measured and Body Mass Index calculated. Only women with a Body Mass Index>34.9kg/m(2) were included. Women were booked for a 100g oral glucose tolerance test before 20 weeks, and if normal, another test at 28 weeks gestation. Main outcomes. Impaired Glucose Tolerance Gestational Diabetes Mellitus. Results. Of the 100 women given an appointment for an oral glucose tolerance test before 20 weeks gestation, 92 attended. Of these, 10 women(10.8%) had an abnormal result with impaired glucose tolerance in 5 cases(5.4%) and gestational diabetes mellitus in 5 cases(5.4%). Of those with a normal result at 20 weeks, 81 attended for a repeat test at 28 weeks gestation. A further 4(4.9%) had impaired glucose tolerance and 4(4.9%) had gestational diabetes mellitus. A total of 18 (20.5%) out of the 88 who complied with screening had an abnormal test. Conclusions. Women who have moderate/severe obesity have a one in five chance of having an abnormal diagnostic oral glucose tolerance test when screened for gestational diabetes mellitus. To optimize maternal glycemic control in pregnancy we suggest that women with a Body Mass Index>34.9 kg/m(2) may need to be screened early in pregnancy and, if the test is normal, again at 28 weeks gestation. |
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Authors:
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Vicky O'Dwyer; Nadine Farah; Jennifer Hogan; Norah O'Connor; Mairead M Kennelly; Michael J Turner |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-15 |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: - ISSN: 1600-0412 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 The Authors AOGS© 2011 Nordic Federation of Societies of Obstetrics and Gynecology. |
Affiliation:
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University College Dublin Centre for Human Reproduction, Coombe Women and Infants University Hospital, Ireland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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