| Timing of life-threatening arrhythmias detected by implantable cardioverter-defibrillators in relation to changes in cosmophysical factors. | |
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MedLine Citation:
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PMID: 18810718 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Studies have linked the natural history of many pathologies with environmental physical activity. This study investigated the relationship between the occurrence of ventricular tachycardia/fibrillation (VT/VF) recorded by implantable cardioverter defibrillators (ICD) and geomagnetic and cosmic ray (neutron) activity. METHODS: The study group included 85 patients (73 men) with cardiomyopathy (80% ischemic) who underwent ICD placement in the years 1995-2006; 74% had a left ventricular ejection fraction of < 30%. Data on the days on which VT/VF occurred (total number of days: 284) and the days on which the patients were treated (total number of treatments: 580) were collected from the ICD records. The findings were analyzed against levels of geomagnetic activity (GMA) (I degree -IV degree) and cosmic ray activity (CRA), derived from international observatories, on the same days and throughout the study period. RESULTS: On days of VT/VF, daily values of GMA level averaged 1.5 +/- 0.7, consistent with level I degree (quiet). The ratios of daily VT/VF episodes and treatment to GMA level for the whole study period were as follows: 1.2 level I; 0.9 level II; 0.69 level III; 0.78 level IV (r = -0.974; p = 0.02). Mean CRA on days of VT/VF was 9246.8 +/- 299.0 imp/min, and for all 4383 days studied, 8805.33 +/- 411.4 imp/min (p < 0.0001). CONCLUSIONS: In patients with predominantly ischemic cardiomyopathy and severe left ventricular dysfunction, VT/VF occurs more often on days of low GMA and high CRA. Further studies are needed to determine the underlying mechanism of the effect of neutron activity on cardiac electrical instability. |
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Authors:
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Elyiahu Stoupel; Jairo Kusniec; Alexander Mazur; Evgeny Abramson; Peter Israelevich; Boris Strasberg |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cardiology journal Volume: 15 ISSN: 1897-5593 ISO Abbreviation: - Publication Date: 2008 |
Date Detail:
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Created Date: 2008-09-23 Completed Date: 2008-12-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101392712 Medline TA: Cardiol J Country: Poland |
Other Details:
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Languages: eng Pagination: 437-40 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Rabin Medical Center, Beilinson Hospital, Petah Tiqwa, Israel. stoupel@inter.net.il |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Cardiomyopathies / complications Cosmic Radiation* Death, Sudden, Cardiac / etiology Defibrillators, Implantable* Female Geological Phenomena Humans Magnetics* Male Middle Aged Myocardial Ischemia / complications Tachycardia, Ventricular / diagnosis*, etiology*, therapy Ventricular Fibrillation / diagnosis, etiology, therapy |
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