Document Detail

Timing of insults causing abnormal outcome in preterm infants 1989-1992.
MedLine Citation:
PMID:  9359438     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to clarify the influence of timing of brain insults causing abnormal outcome in preterm infants. METHODS: One hundred and thirty-one preterm infants were examined. The timing of brain insult was estimated from EEG or clinical findings. Development was assessed until a corrected age of 48 months. RESULTS: 39% and 4% of infants, respectively, born before and after the 28-week time point subsequently died (P < 0.05). Abnormal development was observed in 16% of the first group and 13% of the second (N.S.). None of those born before 28 weeks showed intrauterine injuries while nine of the infants which were born after this time showed intrauterine injuries (P < 0.05). Fetal distress was noted in all infants suffering neonatal death born after 28 weeks. CONCLUSION: Intrauterine brain insult was concluded to be the cause of neonatal death or abnormal development in many infants born after 28 weeks.
S Morikawa; A Itakura; F Hayakawa; S Mizutani; K Matsuzawa; O Kurauchi
Related Documents :
11268718 - Possible strategies to protect the preterm brain against the fetal inflammatory response.
910618 - Intrauterine brain death. neuraxial reticular core necrosis.
8060168 - Cross-placental transfer of organochlorine pesticides in mexican free-tailed bats from ...
15286218 - Brain volumes in adult survivors of very low birth weight: a sibling-controlled study.
22404888 - Rds--cpap or surfactant or both.
6467818 - Transfontanellar ultrasound of term infants.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  59     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1997 Oct 
Date Detail:
Created Date:  1997-12-03     Completed Date:  1997-12-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Brain Injuries / complications*
Fetal Diseases
Gestational Age*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / etiology*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cloning and characterization of a complementary DNA for a thyroid hormone-responsive protein in matu...
Next Document:  Cervicovaginal washing prolactin assay in prediction of preterm delivery.