Document Detail

Timing of delivery for pregnancies with congenital diaphragmatic hernia.
MedLine Citation:
PMID:  21125710     Owner:  NLM     Status:  In-Process    
A recent report has suggested that delivery at early term ages may be associated with lower mortality among infants with congenital diaphragmatic hernia. We sought to confirm this finding by examining gestational age-specific mortality in the USA in term infants with isolated congenital diaphragmatic hernia, delivered following the spontaneous onset of labour. In the final population of 928 infants, neonatal and infant mortality decreased with advancing gestation, from 25 and 36% at 37 weeks of gestation, respectively, to 17 and 20% at 40 weeks of gestation, respectively. Log-binomial regression models showed that neonatal and infant mortality at 37 weeks of gestation were significantly higher than at 40 weeks. Further evidence, ideally from a randomised trial, is needed before recommendations for clinical practice on timing of delivery should be made.
J A Hutcheon; B Butler; S Lisonkova; G P Marquette; C Mayer; A Skoll; K S Joseph
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  117     ISSN:  1471-0528     ISO Abbreviation:  BJOG     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  1658-62     Citation Subset:  AIM; IM    
Department of Obstetrics & Gynaecology, University of British Columbia, Vancouver, BC, Canada.
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Grant Support
//Canadian Institutes of Health Research

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