| Timing of delivery following selective laser photocoagulation for twin-to-twin transfusion syndrome. | |
| | |
MedLine Citation:
|
PMID: 22840722 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVE: We sought to compare intrauterine risks with postnatal outcome in monochorionic pregnancies operated by fetoscopic laser surgery for twin-to-twin transfusion syndrome. STUDY DESIGN: A cohort of 602 consecutive cases was analyzed. Unexpected prenatal adverse events were identified when a fatal or potentially fatal event occurred that could have been avoided by timely delivery. RESULTS: The prospective risk of an unexpected adverse event dropped from 16.8% (95% confidence interval [CI], 13.6-20.5%) to 0% (95% CI, 0-11%) between 26-36 weeks. At 32 weeks, the residual risk was 1 in 17 (95% CI, 1/28-1/11). The perinatal rate of death or severe brain lesions dropped from 35% (25-47%) in infants delivered at 26-28 weeks down to 3% (1-6%) at 34-36 weeks. CONCLUSION: Our results did not identify an optimal cut-off for elective preterm delivery in laser-operated twin-to-twin transfusion syndrome. Perinatal morbidity appears low from ≥32 weeks and the decision for elective delivery should be based upon medical history, parental demand, and expert assessment. |
| | |
Authors:
|
Julien J Stirnemann; Thibault Quibel; Mohammed Essaoui; Laurent J Salomon; Laurence Bussieres; Yves Ville |
Publication Detail:
|
Type: Journal Article Date: 2012-06-23 |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 207 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2012 Aug |
Date Detail:
|
Created Date: 2012-07-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 127.e1-6 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright © 2012 Mosby, Inc. All rights reserved. |
Affiliation:
|
Department of Obstetrics and Maternal-Fetal Medicine, GHU Necker-Enfants Malades, Université Paris Descartes, Paris, France; MAP5 (Laboratory of Applied Mathematics and Statistics) UMR CNRS 8145, Université Paris Descartes, Paris, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Outcomes associated with a structured prenatal counseling program for shoulder dystocia with brachia...
Next Document: Maternal obesity and contraction strength in the first stage of labor.