Document Detail


Timing of birth and infant and early neonatal mortality in Sweden 1973-95: longitudinal birth register study.
MedLine Citation:
PMID:  11739216     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the impact of time of birth on infant mortality and early neonatal mortality in full term and preterm births.
DESIGN: Analysis of data from the Swedish birth register, 1973-95.
PARTICIPANTS: 2 102 324 spontaneous live births of infants without congenital malformation.
OUTCOME MEASUREMENTS: Absolute and relative risk of infant mortality, early neonatal mortality, and early neonatal mortality related to asphyxia.
RESULTS: Infant mortality, early neonatal mortality, and early neonatal mortality related to asphyxia were higher in infants who were born during the night (9 pm to 9 am) compared with those born during the day for 1973-9, 1980-9, and 1990-5. The difference was more dramatic for preterm infants. The largest difference was observed during 1990-5, when there was a 30% increase in early neonatal mortality (relative risk 1.31, 95% confidence interval 1.10 to 1.57) and a 70% increase in early neonatal mortality related to asphyxia (1.70, 1.22 to 2.38) in preterm infants born during the night compared with rates for preterm infants born during the day. A detailed analysis over 24 hours revealed two "high risk" periods: between 5 pm and 1 am and around 9 am.
CONCLUSIONS: Infants born during the night have a greater risk of infant and early neonatal mortality and early neonatal mortality related to asphyxia than those born during the day. There has been no improvement over the past two decades. The problem is more serious for preterm births and was even worse in the 1990s. Shift changes and the hours immediately after such changes are high risk periods for neonatal care.
Authors:
Z C Luo; J Karlberg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  BMJ (Clinical research ed.)     Volume:  323     ISSN:  0959-8138     ISO Abbreviation:  BMJ     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-12     Completed Date:  2002-01-15     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  8900488     Medline TA:  BMJ     Country:  England    
Other Details:
Languages:  eng     Pagination:  1327-30     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Asphyxia Neonatorum / mortality
Female
Humans
Infant Mortality*
Infant, Newborn
Infant, Premature
Labor, Obstetric*
Longitudinal Studies
Pregnancy
Registries
Risk Factors
Sweden / epidemiology
Time Factors
Comments/Corrections

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