Document Detail

Timing of indicated late-preterm and early-term birth.
MedLine Citation:
PMID:  21775849     Owner:  NLM     Status:  MEDLINE    
The growing public health awareness of prematurity and its complications has prompted careful evaluation of the timing of deliveries by clinicians and hospitals. Preterm birth is associated with significant morbidity and mortality, and affects more than half a million births in the United States each year. In some situations, however, a late-preterm or early-term birth is the optimal outcome for the mother, child, or both owing to conditions that can result in worse outcomes if pregnancy is allowed to continue. These conditions may be categorized as placental, maternal, or fetal, including conditions such as placenta previa, preeclampsia, and multiple gestations. Some risks associated with early delivery are common to all conditions, including prematurity-related morbidities (eg, respiratory distress syndrome and intraventricular hemorrhage) as well as maternal intrapartum morbidities such as failed induction and cesarean delivery. However, when continuation of the pregnancy is associated with more risks such as hemorrhage, uterine rupture, and stillbirth, preterm delivery maybe indicated. In February 2011, the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the Society for Maternal-Fetal Medicine held a workshop titled "Timing of Indicated Late Preterm and Early Term Births." The goal of the workshop was to synthesize the available information regarding conditions that may result in medically indicated late-preterm and early-term births to determine the potential risks and benefits of delivery compared with continued pregnancy, determine the optimal gestational age for delivery of affected pregnancies when possible, and inform future research regarding these issues. Based on available data and expert opinion, optimal timing for delivery for specific conditions was determined by consensus.
Catherine Y Spong; Brian M Mercer; Mary D'alton; Sarah Kilpatrick; Sean Blackwell; George Saade
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  118     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-21     Completed Date:  2011-09-21     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  323-33     Citation Subset:  AIM; IM    
Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland 20892, USA.
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MeSH Terms
Delivery, Obstetric*
Fetal Organ Maturity / drug effects
Gestational Age
Glucocorticoids / administration & dosage
Infant, Newborn
Obstetric Labor Complications*
Pregnancy Complications
Premature Birth* / etiology
Risk Factors
Term Birth
Time Factors
Grant Support
Reg. No./Substance:
Comment In:
Obstet Gynecol. 2012 Jan;119(1):183-4; author reply 184-5   [PMID:  22183232 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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