| Time to extubation in infants undergoing pyloromyotomy -- isoflurane inhalation vs remifentanil infusion. | |
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MedLine Citation:
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PMID: 19583078 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Infantile hypertrophic pyloric stenosis (IHPS) associated with metabolic alkalosis, could induce late anesthesia recovery, especially when opioids are used. The aim of this study was to compare the time of extubation and the quality of perioperative analgesia in infants scheduled for pyloromyotomy, receiving either isoflurane inhalation or remifentanil infusion. METHODS: Thirty full-term infants scheduled for pyloromyotomy were prospectively studied. A standardized anesthetic induction was performed. For maintenance of anesthesia, infants were randomly allocated to receive either isoflurane 0.75% of inspired concentration (GI n = 15), or remifentanil as a continuous infusion of 0.4 microg x kg(-1) x mn(-1) (GR n = 15). At the beginning of skin closure, the anesthetic was discontinued and 15 mg x kg(-1) of paracetamol administered. Non parametric tests were used in statistical analysis. RESULTS: The time to extubation was similar in both groups. The intraoperative heart rate was significantly lower in the GR group. CONCLUSION: Remifentanil provided better intraoperative analgesia than isoflurane in infants undergoing pyloromyotomy without increasing time to extubation. |
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Authors:
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Sonia Ben Khalifa; Sami Blidi; Mehdi Trifa; Alia Skhiri; Mehdi Drira; Tarek Regaya; Amjed Fekih Hassen |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Middle East journal of anesthesiology Volume: 20 ISSN: 0544-0440 ISO Abbreviation: Middle East J Anesthesiol Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-07-08 Completed Date: 2009-08-04 Revised Date: 2013-04-25 |
Medline Journal Info:
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Nlm Unique ID: 8604187 Medline TA: Middle East J Anesthesiol Country: Lebanon |
Other Details:
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Languages: eng Pagination: 277-80 Citation Subset: IM |
Affiliation:
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Department of Anesthesia and Intensive Care, Children's Hospital, Tunis. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acetaminophen
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therapeutic use Analgesics, Non-Narcotic / therapeutic use Anesthetics, Inhalation / therapeutic use Anesthetics, Intravenous / therapeutic use* Female Heart Rate / drug effects Humans Infant Infant, Newborn Intubation, Intratracheal Isoflurane / therapeutic use* Male Perioperative Care Piperidines / therapeutic use* Prospective Studies Pyloric Stenosis, Hypertrophic / surgery Single-Blind Method Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Non-Narcotic; 0/Anesthetics, Inhalation; 0/Anesthetics, Intravenous; 0/Piperidines; 103-90-2/Acetaminophen; 26675-46-7/Isoflurane; P10582JYYK/remifentanil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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