Document Detail


Time-resolved computed tomography imaging of the aorta: a feasibility study.
MedLine Citation:
PMID:  20463535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The aim of this study was to test the feasibility and the additional value of time-resolved computed tomography angiography (CTA) of the aorta, using multiple low-dose phases. MATERIALS AND METHODS: Twenty-two consecutive patients underwent a time-resolved CTA protocol (TR-CTA) of the aorta, either for follow-up of endovascular aneurysm repair (EVAR) or aortic dissection, using a CT scanner with the possibility of bidirectional table movements for dynamic CT imaging (Siemens Definition AS+; 12 phases, temporal resolution 2.5 s/scan, 80 kVp, 120 mAs/rot, scan range 27 cm, 60 mL; Imeron 400, flow 5.0 mL/s). The patients had previously undergone standard CTA (120 kVp, 100 mL contrast agent). Standard CTA after EVAR and aortic dissection were triphasic and biphasic protocols, respectively. Effective radiation dose and maximum Hounsfield unit values were compared between the TR-CTA and standard CTA. Image quality was rated for TR-CTA. RESULTS: Fifteen patients underwent TR-CTA for follow-up after EVAR; 4 were examined for follow-up after dissection and 3 for both, that is, aortic dissection treated with an endovascular stent. Mean effective dose of TR-CTA for the scan range of 27 cm (15.3+/-1.1 mSv) was comparable with the biphasic standard CTA protocols (16.2+/-2.4 mSv; P=0.29). Triphasic protocols resulted in 23.7+/-4.9 mSv (P<0.0001). Hounsfield unit values were not significantly different. Most of the examinations (91%) were fully evaluable, whereas 9% were of limited evaluability because of high image noise. None of the examinations was nondiagnostic. DISCUSSION: TR-CTA consisting of multiple low-dose phases leads to a clear depiction of the angiographic information and is feasible for follow-up after EVAR and aortic dissection. Considering the limited scan range, radiation dose is comparable with the standard biphasic CTA protocol, but dynamic information may provide additional information.
Authors:
Wieland H Sommer; Dirk A Clevert; Fabian Bamberg; Andreas Helck; Edda Albrecht; Maximilian F Reiser; Christoph R Becker; Konstantin Nikolaou
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of thoracic imaging     Volume:  25     ISSN:  1536-0237     ISO Abbreviation:  J Thorac Imaging     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-13     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606160     Medline TA:  J Thorac Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  161-7     Citation Subset:  IM    
Affiliation:
Department of Clinical Radiology, University Hospitals-Grosshadern, Ludwig-Maximilians University, Munich, Germany. wieland.sommer@med.uni-muenchen.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Aneurysm, Dissecting / radiography*,  surgery
Aortic Aneurysm / radiography*,  surgery
Contrast Media
Feasibility Studies
Female
Humans
Male
Postoperative Complications / radiography*
Radiation Dosage
Radiographic Image Interpretation, Computer-Assisted
Statistics, Nonparametric
Time Factors
Tomography, X-Ray Computed / methods*
Chemical
Reg. No./Substance:
0/Contrast Media

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