Document Detail

Time length of negativization of hCG serum values after either surgical or medical treatment of ectopic pregnancy.
MedLine Citation:
PMID:  9785922     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to compare the time length until the human chorionic gonadotropin titer became negative after medical or surgical treatment of ectopic pregnancy. EXPERIMENTAL DESIGN: Prospective, randomized study. PARTECIPANTS AND INTERVENTIONS: We compared time to resolution in 30 cases of tubal pregnancies successfully treated, 15 underwent laparoscopic linear salpingostomy (group 1) and 15 medical treatment with single-ose methotrexate (group 2). The patients of both groups had no meaningful differences of age, gestational age and human chorionic gonadotropin mean values. MEASURES: During the follow-up human chorionic gonadotropin serum values were obtained every two days until the titer was negative. RESULTS: The time to resolution was 33.6 +/- 6.6 days in group 1, 31.5 +/- 7.8 in group 2 with no statistically meaningful differences. CONCLUSION: The data, comparable with results obtained by laparoscopic treatment, suggest that human chorionic gonadotropin value becomes negative independently of type of treatment and residual trophoblast.
N Colacurci; P De Franciscis; R Zarcone; N Fortunato; M Passaro; A Mollo; G Russo
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Panminerva medica     Volume:  40     ISSN:  0031-0808     ISO Abbreviation:  Panminerva Med     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-11-05     Completed Date:  1998-11-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421110     Medline TA:  Panminerva Med     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  223-5     Citation Subset:  IM    
Department of Gynecology and Obstetrics, School of Medicine, Second University of Naples, Italy.
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MeSH Terms
Abortifacient Agents, Nonsteroidal / therapeutic use*
Chorionic Gonadotropin / blood*
Follow-Up Studies
Methotrexate / therapeutic use*
Pregnancy, Ectopic / blood*,  drug therapy,  therapy*
Prospective Studies
Salpingostomy / methods
Time Factors
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 0/Chorionic Gonadotropin; 59-05-2/Methotrexate

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