| Time-lapse analysis of laser phase shift for noninvasive discrimination of human normal cells and malignant tumor cells. | |
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MedLine Citation:
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PMID: 22738695 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Time-lapse analysis of phase shift using phase-shifting laser microscopy (PLM) revealed that the laser phase shifts of primary normal human prostate epithelial cells (PRECs) and human prostatic carcinoma epithelial cell line (PC-3) cells during the mitotic phase were markedly higher than those in the interphase. The phase shift of PC-3 cells during the interphase was markedly lower than that of PRECs throughout the cell cycle. In conclusion, it was proposed that adherent PC-3 cancer cells could be noninvasively discriminated from normal adherent PRECs by the periodical measurement of phase shift using PLM during culture. |
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Authors:
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Mutsumi Takagi; Yuhei Shibaki |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-26 |
Journal Detail:
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Title: Journal of bioscience and bioengineering Volume: - ISSN: 1347-4421 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-6-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888800 Medline TA: J Biosci Bioeng Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Division of Biotechnology and Macromolecular Chemistry, Graduate School of Engineering, Hokkaido University, N13W8 Kita-ku, Sapporo 060-8628, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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