Document Detail

Time-dependent variations of transcutaneous PCO2 level in normal subjects.
MedLine Citation:
PMID:  3134327     Owner:  NLM     Status:  MEDLINE    
Transcutaneous PCO2 (PtcCO2), which is linearly related to arterial PCO2, was continuously recorded in healthy, adult, normal volunteers for 8-h periods. Recording this variable with the apparatus employed permits measurement of changes in the level of ventilation while subjects are freely ambulant and unencumbered by invasive and flow-resistive respiratory apparatus. The time series obtained exhibited marked periodicities. The frequencies and amplitudes varied between subjects. Peak-to-peak variation was 10-20% of mean values. There was no apparent association between fluctuations in PCO2 and activity other than formal exercise. Visual inspection of the time series and preliminary statistical analysis of digitally converted data suggested that the time-dependent changes of PtcCO2 were normally distributed. However, more rigorous statistical examination revealed that in no case was PtcCO2 actually normally distributed.
D Pilsbury; G Hibbert
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  64     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-08-17     Completed Date:  1988-08-17     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1858-63     Citation Subset:  IM    
Oxford University, Department of Psychiatry, Warneford Hospital, United Kingdom.
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MeSH Terms
Carbon Dioxide / blood*
Skin Physiological Phenomena
Time Factors
Reg. No./Substance:
124-38-9/Carbon Dioxide

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